UHPLC Analysis of Saffron (Crocus sativus L.): Optimization of Separation Using Chemometrics and Detection of Minor Crocetin Esters
نویسندگان
چکیده
منابع مشابه
Effects of Crocetin Esters and Crocetin from Crocus sativus L. on Aortic Contractility in Rat Genetic Hypertension.
BACKGROUND Endothelial dysfunction, characterized by an enhancement in vasoconstriction, is clearly associated with hypertension. Saffron (Crocus sativus L.) bioactive compounds have been recognized to have hypotensive properties. Recently, we have reported that crocetin exhibits potent vasodilator effects on isolated aortic rings from hypertensive rats. In this work, we have aimed to analyze t...
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From ancient times, saffron dried stigmas of Crocus sativus L. is widely used as a drug against different human diseases. In the beginning of 1990 ́s scientific literature reported for the first time the antitumor activity of saffron. During the last decade different laboratories of the world (including ours) have accumulated sufficient scientific evidence to suggest that saffron, and its main i...
متن کاملCancer chemopreventive and tumoricidal properties of saffron (Crocus sativus L.).
Since cancer is the most common cause of death in the world population, the possibility that readily available natural substances from plants, vegetables, herbs, and spices may be beneficial in the prevention of cancer warrants closer examination. Saffron in filaments is the dried, dark red stigmata of Crocus sativus L. flowers and it is used as a spice, food colorant, and a drug in medicine. A...
متن کاملBiological Properties and Medicinal Use of Saffron (Crocus sativus L
From ancient times, the saffron Crocus sativus L. is widely used as drug to promote health and fight disease, especially in the Middle East and Southeast Asia. Saffron is cultivated in different parts of the world, but currently mainly in Iran. In view of its wide range of medical uses, the saffron has under gone extensive phytochemical and biochemical studies and variety of biologically active...
متن کاملAFLP and MS-AFLP Analysis of the Variation within Saffron Crocus (Crocus sativus L.) Germplasm
The presence and extent of genetic variation in saffron crocus are still debated, as testified by several contradictory articles providing contrasting results about the monomorphism or less of the species. Remarkably, phenotypic variations have been frequently observed in the field, such variations are usually unstable and can change from one growing season to another. Considering that gene exp...
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ژورنال
عنوان ژورنال: Molecules
سال: 2018
ISSN: 1420-3049
DOI: 10.3390/molecules23081851